Method developed to detect PFAS in “under three minutes”

A group of researchers from the New Jersey Institute of Technology (NJIT) have developed a method to detect “forever chemicals” from food packaging material, water and social samples in “three minutes or less”.

Per- and poly-fluoroalkyl substances (PFAS), are man-made compounds that can take thousands of years to degrade. They can be found in various daily objects including grease-resistant food packaging and water-repellent clothing.

According to the scientists, PFAS has made its way “nearly half the US tap water supply”, sparking significant food safety concerns.

The new study was featured in Elsevier’s Journal of Hazardous Materials, and allowed chemists to demonstrate a new lab-based method to detect traces of PFAS in “one of the fastest and most sensitive approaches yet”.

Researchers have claimed that their approach could “significantly speed up efforts to study and address the bioaccumulation of PFAS in the environment”.

The study garnered more than $2 billion of EPA grant funding from President Biden’s Bipartisan Infrastructure Law for states to conduct water quality testing and treatment for the emerging contaminants.

“There are thousands of different species of PFAS, but we’ve yet to understand the extent of their distribution in our environment because the current testing methods are costly and time-consuming, taking hours for sample preparation and analysis in some cases,” said Hao Chen, the study’s Corresponding Author and NJIT Chemistry Professor.

“What our study demonstrates is a much faster, sensitive and versatile method that can monitor our drinking water, land and consumer products for contamination in minutes.”

The chemists have shared that their new testing method involves an ionisation technique for analysing the molecular composition of sample materials called paper spray mass spectrometry (PS-MS) and claim it is 10-100 times more sensitive than the current standard technique for PFAS testing, liquid chromatography/mass spectrometry.

“PFAS can be ionized and rapidly detected by a high-resolution mass spectrometer, which gives a clear view of each PFAS species present and the degree of contamination down to a parts-per-trillion (ppt) level. For more complex matrices like soil, we’ve applied a related method called desalting paper spray mass spectrometry (DPS-MS) that washes away salts which normally suppress the ion signal of PFAS. Together, they greatly improve our ability to detect these compounds,” continued Chen.

“Our limit of detection for PFAS is roughly 1ppt. For context, this amount has been likened to a drop of water in 20 Olympic-sized swimming pools,” added Md Tanim-Al Hassan, the paper’s first author and Ph.D. chemistry student at NJIT.

Throughout their tests, the team of scientists were able to detect PFAS in “one minute or less” by analysing pieces of various food packaging materials directly, including microwave popcorn paper, instant noodle boxes, and fry and burger packaging from two multinational fast food restaurant chains.

The study results revealed traces of 11 different PFAS molecules — including common types that have been linked to increased cancer risk and immune system suppression, such PFOA (Perfluorooctanoic Acid) and PFOS (Perfluorooctanesulfonic acid).

Meanwhile, in their water analysis, the team detected traces of PFOA in samples of local tap water in under two minutes, while finding no traces of PFAS in samples taken from the university’s filtered fountain water.

PFAS contamination found in processed meats, teas and packaging

“The EPA has already proposed to establish maximum contamination levels (MCLs) for six PFAS in drinking water nationwide, and PFOA and PFOS are among them. This analytical method could facilitate more intensive screenings for toxic PFAS that may be needed under such a proposal to protect the safety of our water supply,” said Mengyan Li, study Co-Author and NJIT Associate Professor of Environmental Sciences.

Going further, the team used DPS-MS, to identified two species of PFAS from 40mg of soil in under three minutes.

Now, the researchers’ rapid detection method is being tested for use alongside cutting-edge techniques for remediating PFAS that are being developed at NJIT’s BioSMART Center.

“Remarkably, in our lab we were able to couple this analytical method to a novel degradation catalyst, which degrades 98.7 percent of PFAS in drinking water samples within three hours. This work may have a national impact, but the immediate effect will be felt in the Northeast area. Roughly 10 percent of 9.2 million New Jersians have high levels of perfluorooctanoic acid in their drinking water compared to the national average of 1.9 percent,” said Wunmi Sadik, study co-author and chair of NJIT’s Department of Chemistry and Environmental Sciences.

Looking to the future, Chen shared that they believe the advance “could also have a swift impact on the monitoring of consumer products, from cosmetics and medicine to fresh and processed foods”. As well as this, the team plans to demonstrate the method’s capabilities for air monitoring.

“Near term, this could be extremely useful for ensuring the safety of food products … it may allow farming produce to be more efficiently monitored for PFAS contamination for example. Our method may also advance the study of airborne PFAS in a similar way to what we’ve demonstrated in this study, which would further help us address this widespread environmental issue,” concluded Chen.