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Liquid chromatography–mass spectrometry (LC-MS)

 

whitepaper

Whitepaper: Advanced mycotoxin testing system

1 June 2012 | By ToxiMet

The analytical resource, expertise, cost and time that is invested into the mycotoxin testing of foods is enormous. The ToxiMet system is a simple, affordable, rugged and reliable system that can accurately and rapidly measure mycotoxin levels at every step in the supply chain without the need of a highly…

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LCMS as a reliable tool for monitoring food allergens contamination

1 May 2012 | By Linda Monaci, National Research Council of Italy (ISPA-CNR)

Food allergen research has considerably expanded its field of interest in recent years probably due to the increasing incidence of food allergies throughout the population. According to the last legislation issued on this issue, there is a current trend to develop reliable methods tailored to the detection of food allergens…

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Rapid and automated screening of priority β-agonists in urine using high resolution LC-MS technology

6 September 2011 | By Thorsten Bernsmann and Peter Fürst, Chemical and Veterinary Analytical Institute, and Michal Godula, Thermo Fisher Scientific

Beta-agonists (β-agonists) are synthetically produced compounds that are widely known for their bronchodilatory and tocolytic effects. At higher doses, these substances also have anabolic effects and can promote live weight gain in food producing animals. Clenbuterol is the most commonly used β-agonist for growth-promoting purposes, despite the fact that there…

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Specific migration of plasticisers coming from closure gaskets: The LC-MS direction

3 March 2011 | By Michele Suman, Food Chemistry and Safety Research Manager, Barilla Food Research Labs

PVC gaskets seals are used for packaging many food commodities (e.g. sauces, vegetables in oil, baby food) in glass jars with metal twist closures, preventing microbiological contamination and providing an easy opening at the same time. The plastisols consist of poly(vinyl chloride) (PVC) usually containing 25 – 45 per cent…

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Using LC-MS to study the fate of food ingredients in the human body

12 May 2010 | By Christian H. Grün & Hans-Gerd Janssen, Unilever Research and Development, Advanced Measurement & Data Modelling

The human body is designed for effectively extracting nutrients from the food we eat. The nutrients provide the body with energy, but in addition, they also provide the building blocks for cell growth. More recently, it has also been realised that specific food ingredients can be associated with a direct…

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LC-MS/MS based quantitative methods for multiple mycotoxins in food

20 February 2009 | By Michael Sulyok, Rainer Schuhmacher & Rudolf Krska, Centre for Analytical Chemistry, Department for Agrobiotechnology, IFA Tulln, University of Natural Resources and Applied Life Sciences Vienna

Since the introduction of atmospheric pressure ionisation liquid chromatography-mass spectrometry (API-LC-MS) in the early 1990s, there was a continuous effort to further improve the performance of the LC-MS instruments concerning sensitivity and robustness. One result of this development is the trend towards methods that are designed to simultaneously analyse a…

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A farm to fork approach to lower acrylamide in food

13 June 2008 | By Frédéric Mestdagh and Bruno De Meulenaer, Department of Food Safety and Food Quality, Faculty of Bioscience Engineering, Ghent University, Belgium

In 2002, Swedish researchers discovered that within certain foods, significant levels of acrylamide, a probable human carcinogen formed during heating processes such as frying, roasting or baking. Free asparagine and reducing sugars were indicated as the most important precursors. Over the past few years, significant progress has been made to…

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Liquid Chromatography-Mass Spectrometry in food analysis

28 February 2008 | By Dr. Mark Buecking, Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Germany

The determination of organic trace compounds in food analysis is of major importance for food quality and food safety aspects. Both the separation of the analyte from potential inferences in the food matrix, as well as the qualitative and quantitative determination of the target compound, are vital steps in analytical…

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Mycotoxin determination in foodstuffs

7 March 2007 | By S. Monbaliu, S. De Saeger and C. Van Peteghem, Ghent University, Laboratory of Food Analysis

This article focuses on the main principle of the liquid chromatographic tandem mass spectrometric (LC-MS/MS) determination of mycotoxins in foodstuffs. It also provides an overview of recent developments in mycotoxin analysis.

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LC-MS/MS for safer seafood

3 May 2005 | By Kevin J. James, Mary Lehane, Brett Hamilton, Ambrose Furey, PROTEOBIO, Mass Spectrometry Centre for Proteomics and Biotoxin Research, Department of Chemistry, Cork Institute of Technology

Toxin contamination has forever been the curse on shellfish production worldwide. Dr Kevin J. James demonstrates how new technology can protect the health of shellfish lovers. PROTEOBIO is at the forefront of food-borne biotoxin research in Europe and specialises in the development of novel methods to address the complex questions…