Determination of 208 pesticide residues and their metabolites in foods using Oasis PRiME HLB and Xevo TQ-GC

Gas chromatography-mass spectrometry (GC-MS) has been a common analytical method for pesticide measurement due to its high efficiency of separation, along with its qualitative and quantitative performance.

As a milestone of pesticides analysis, Lehotay¹ and Nguyen, et al.² established a sample preparation method based on QuEChERS technology in 2015 for the simultaneous detection of multiple pesticide residues in vegetables and other foods using LC-MS/MS and GC-MS/MS. In recent years GC-MS/MS analysis has become the preferred method for pesticides analysis due to its advantages in selectivity, sensitivity, high throughput, and accurate quantitative performance.³

Recently, the first Chinese National Standard Method (GB 23200.113-2018)⁴ for multiple pesticide residues using GC-MS/MS was released. For the first time in GB methodology, two efficient technologies have been adopted: QuEChERS for sample extraction, and GC-MS/MS for detection.